Analysis of dementia EEG signals using empirical mode decomposition variants and deep learning
1 Department of Electrical and Electronics Engineering, Izmir University of Economics, Izmir, Turkey
2 Department of Biomedical Engineering, Izmir Katip Celebi University, Izmir, Turkey
Abstract

In recent years, Alzheimer’s dementia (AD) is the most common neurological condition caused by electrical activity changes in the human brain. The diagnosis of AD can be provided by using medical devices such as electroencephalography (EEG). In this study, EEG signals of AD patients and healthy control subjects were analyzed. Advanced signal decomposition methods, which are empirical mode decomposition (EMD) and ensemble empirical mode decomposition (EEMD), were used to further investigate EEG signals. The first three intrinsic mode functions (IMFs) were obtained using the EMD and EEMD methods. Spectral and time-domain features were extracted from IMFs and raw EEG signals. Then, topographical heat maps were generated from these features. Topographic Feature Map (Topo-map) were classified using a two-dimensional convolutional neural network (2D-CNN). Different CNN architectures were compared in terms of performance, including EfficientNet-b0, Resnet-50, and Resnet-18. The experimental results demonstrate that the proposed approach effectively captures the spatial and spectral characteristics of EEG signals associated with Alzheimer’s disease. 95.98% classification accuracy was achieved with the EfficienNet-b0 architecture.

Keywords

Alzheimer dementia (AD); electroencephalography (EEG); empirical mode decomposition (EMD); ensemble empirical mode decomposition; convolutional neural network (CNN); intrinsic mode functions (IMFs)

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